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Wednesday, November 5, 2025

NHS Trials 15-Minute Sepsis Blood Test for Children

Key Takeaways

  • NHS trials 15-minute blood test to distinguish bacterial vs viral infections in children
  • Test could dramatically speed up sepsis diagnosis and antibiotic treatment
  • Currently being tested at three major children’s hospitals across England
  • Experts say innovation could save dozens of young lives annually

The NHS is trialling a revolutionary 15-minute blood test that could rapidly diagnose life-threatening conditions like sepsis and meningitis in children. This breakthrough technology can quickly determine whether young patients have bacterial or viral infections, enabling doctors to administer antibiotics within the critical treatment window.

Unlike traditional blood tests that take hours and require lab analysis, this new test provides immediate results at the bedside. In sepsis cases, where patients need antibiotics within one to six hours of hospital arrival, this speed could be life-saving. Delayed treatment can lead to septic shock and organ failure.

Doctors involved in the trial have already witnessed positive outcomes. One child with meningococcal meningitis received faster treatment, while another with sepsis started antibiotics immediately.

With approximately 25,000 UK children affected by sepsis annually, this innovation addresses a critical healthcare gap.

Nationwide Hospital Trials

NHS England has funded the technology trial across three emergency departments: Alder Hey Children’s Hospital in Liverpool, St Mary’s Hospital in London, and Great North Children’s Hospital in Newcastle.

Professor Enitan Carrol, leading the project from the University of Liverpool, explained: ‘Many children arriving at hospital have fever. This test quickly distinguishes between minor viral illnesses like colds and serious infections.’

‘Our study investigates whether this definitive test will help doctors make faster decisions and reduce unnecessary antibiotic use – benefiting both patients and the NHS.’

Expert Endorsements

Dr Ron Daniels of the UK Sepsis Trust emphasized the test’s potential to ‘save dozens of young lives every year.’ He noted that severe infections represent ‘one of the greatest acute illness burdens facing our NHS,’ while antibiotic resistance from overprescribing affects thousands.

‘Using antibiotics more wisely – withholding them where ineffective and administering them urgently where needed – has never been more important,’ Dr Daniels added.

He also highlighted that while the current study focuses on children, previous research shows the test performs even better in adults, suggesting broader applications.

Professor Simon Kenny, NHS England’s national clinical director for children, stated: ‘Innovations like the 15-minute blood test speed up diagnosis and allow focused treatment while freeing resources. It’s excellent we’re trialling this during winter when the NHS is busiest.’

Dr Emma Lim from Great North Children’s Hospital noted: ‘Thousands of worried parents bring feverish children to hospital annually. While often not serious, it’s difficult to assess immediately. A reliable rapid test helps faster decision-making and reduces unnecessary antibiotics, benefiting patients, parents and the NHS.’

The study examining the MeMed BV test will continue until March.

Recognizing Sepsis: Critical Signs

Sepsis occurs when the body’s infection-fighting chemicals damage its own tissues and organs, potentially causing shock, organ failure and death. Early recognition and treatment are crucial.

Remember the ‘SEPSIS’ acronym for major warning signs:

  • Slurred speech, confusion, lethargy or disorientation
  • Extreme shivering, muscle pain, fever or low temperature
  • Persistent rash that doesn’t fade when pressed
  • Severe breathlessness or rapid breathing
  • Inability to pass urine for several hours
  • Skin that appears mottled or discoloured

Children may experience convulsions or non-fading rashes, with over 40% of cases occurring in under-fives. Early symptoms often resemble gastro, flu or chest infections. If concerned, seek immediate medical help and specifically ask: ‘Could this be sepsis?’

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